2008 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 7 | vs | SEA | W | 34-10 | Ralph Wilson Stadium |
| 2 | Sep 14 | @ | JAX | W | 20-16 | Jacksonville Municipal Stadium |
| 3 | Sep 21 | vs | Oakland Raiders | W | 24-23 | Ralph Wilson Stadium |
| 4 | Sep 28 | @ | St. Louis Rams | W | 31-14 | Edward Jones Dome |
| 5 | Oct 5 | @ | ARI | L | 17-41 | University of Phoenix Stadium |
| 7 | Oct 19 | vs | San Diego Chargers | W | 23-14 | Ralph Wilson Stadium |
| 8 | Oct 26 | @ | MIA | L | 16-25 | Dolphin Stadium |
| 9 | Nov 2 | vs | NYJ | L | 17-26 | Ralph Wilson Stadium |
| 10 | Nov 9 | @ | NE | L | 10-20 | Gillette Stadium |
| 11 | Nov 17 | vs | CLE | L | 27-29 | Ralph Wilson Stadium |
| 12 | Nov 23 | @ | KC | W | 54-31 | Arrowhead Stadium |
| 13 | Nov 30 | vs | SF | L | 3-10 | Ralph Wilson Stadium |
| 14 | Dec 7 | vs | MIA | L | 3-16 | Rogers Centre |
| 15 | Dec 14 | @ | NYJ | L | 27-31 | Giants Stadium |
| 16 | Dec 21 | @ | DEN | W | 30-23 | Invesco Field at Mile High |
| 17 | Dec 28 | vs | NE | L | 0-13 | Ralph Wilson Stadium |