SF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Shaun Hill | 14/23 | 161 | 1 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Frank Gore | 24 | 66 | 0 |
| Shaun Hill | 4 | 0 | 0 |
| Jason Hill | 1 | -4 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Isaac Bruce | 5/5 | 67 | 1 |
| Jason Hill | 5/5 | 55 | 0 |
| Frank Gore | 3/3 | 23 | 0 |
| Bryant Johnson | 1/1 | 16 | 0 |
BUF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Trent Edwards | 10/21 | 112 | 0 | 0 |
| J.P. Losman | 11/17 | 93 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Marshawn Lynch | 16 | 134 | 0 |
| Roscoe Parrish | 1 | 9 | 0 |
| Fred Jackson | 5 | 8 | 0 |
| Trent Edwards | 3 | 5 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Lee Evans | 7/7 | 80 | 0 |
| Josh Reed | 5/5 | 58 | 0 |
| Derek Schouman | 4/4 | 44 | 0 |
| Fred Jackson | 2/2 | 13 | 0 |
| Roscoe Parrish | 2/2 | 9 | 0 |
| Marshawn Lynch | 1/1 | 1 | 0 |