2008 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 7 | vs | CAR | L | 24-26 | Qualcomm Stadium |
| 2 | Sep 14 | @ | DEN | L | 38-39 | Invesco Field at Mile High |
| 3 | Sep 22 | vs | NYJ | W | 48-29 | Qualcomm Stadium |
| 4 | Sep 28 | @ | Oakland Raiders | W | 28-18 | Oakland-Alameda County Coliseum |
| 5 | Oct 5 | @ | MIA | L | 10-17 | Dolphin Stadium |
| 6 | Oct 12 | vs | NE | W | 30-10 | Qualcomm Stadium |
| 7 | Oct 19 | @ | BUF | L | 14-23 | Ralph Wilson Stadium |
| 8 | Oct 26 | @ | NO | L | 32-37 | Wembley Stadium |
| 10 | Nov 9 | vs | KC | W | 20-19 | Qualcomm Stadium |
| 11 | Nov 16 | @ | PIT | L | 10-11 | Heinz Field |
| 12 | Nov 23 | vs | IND | L | 20-23 | Qualcomm Stadium |
| 13 | Nov 30 | vs | ATL | L | 16-22 | Qualcomm Stadium |
| 14 | Dec 4 | vs | Oakland Raiders | W | 34-7 | Qualcomm Stadium |
| 15 | Dec 14 | @ | KC | W | 22-21 | Arrowhead Stadium |
| 16 | Dec 21 | @ | TB | W | 41-24 | Raymond James Stadium |
| 17 | Dec 28 | vs | DEN | W | 52-21 | Qualcomm Stadium |