2000 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 3 | vs | Tennessee Titans | W | 16-13 | Ralph Wilson Stadium |
| 2 | Sep 10 | vs | GB | W | 27-18 | Ralph Wilson Stadium |
| 3 | Sep 17 | @ | NYJ | L | 14-27 | Giants Stadium |
| 5 | Oct 1 | vs | IND | L | 16-18 | Ralph Wilson Stadium |
| 6 | Oct 8 | @ | MIA | L | 13-22 | Pro Player Stadium |
| 7 | Oct 15 | vs | San Diego Chargers | W | 27-24 OT | Ralph Wilson Stadium |
| 8 | Oct 22 | @ | MIN | L | 27-31 | Hubert H. Humphrey Metrodome |
| 9 | Oct 29 | vs | NYJ | W | 23-20 | Ralph Wilson Stadium |
| 10 | Nov 5 | @ | NE | W | 16-13 OT | Foxboro Stadium |
| 11 | Nov 12 | vs | CHI | W | 20-3 | Ralph Wilson Stadium |
| 12 | Nov 19 | @ | KC | W | 21-17 | Arrowhead Stadium |
| 13 | Nov 26 | @ | TB | L | 17-31 | Raymond James Stadium |
| 14 | Dec 3 | vs | MIA | L | 6-33 | Ralph Wilson Stadium |
| 15 | Dec 11 | @ | IND | L | 20-44 | RCA Dome |
| 16 | Dec 17 | vs | NE | L | 10-13 OT | Ralph Wilson Stadium |
| 17 | Dec 23 | @ | SEA | W | 42-23 | Husky Stadium |