2005 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 11 | vs | DAL | L | 24-28 | Qualcomm Stadium |
| 2 | Sep 18 | @ | DEN | L | 17-20 | Invesco Field at Mile High |
| 3 | Sep 25 | vs | NYG | W | 45-23 | Qualcomm Stadium |
| 4 | Oct 2 | @ | NE | W | 41-17 | Gillette Stadium |
| 5 | Oct 10 | vs | PIT | L | 22-24 | Qualcomm Stadium |
| 6 | Oct 16 | @ | Oakland Raiders | W | 27-14 | McAfee Coliseum |
| 7 | Oct 23 | @ | PHI | L | 17-20 | Lincoln Financial Field |
| 8 | Oct 30 | vs | KC | W | 28-20 | Qualcomm Stadium |
| 9 | Nov 6 | @ | NYJ | W | 31-26 | Giants Stadium |
| 11 | Nov 20 | vs | BUF | W | 48-10 | Qualcomm Stadium |
| 12 | Nov 27 | @ | Washington Redskins | W | 23-17 OT | FedExField |
| 13 | Dec 4 | vs | Oakland Raiders | W | 34-10 | Qualcomm Stadium |
| 14 | Dec 11 | vs | MIA | L | 21-23 | Qualcomm Stadium |
| 15 | Dec 18 | @ | IND | W | 26-17 | RCA Dome |
| 16 | Dec 24 | @ | KC | L | 7-20 | Arrowhead Stadium |
| 17 | Dec 31 | vs | DEN | L | 7-23 | Qualcomm Stadium |