2022 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 11 | vs | KC | L | 21-44 | State Farm Stadium |
| 2 | Sep 18 | @ | Las Vegas Raiders | W | 29-23 OT | Allegiant Stadium |
| 3 | Sep 25 | vs | Los Angeles Rams | L | 12-20 | State Farm Stadium |
| 4 | Oct 2 | @ | CAR | W | 26-16 | Bank of America Stadium |
| 5 | Oct 9 | vs | PHI | L | 17-20 | State Farm Stadium |
| 6 | Oct 16 | @ | SEA | L | 9-19 | Lumen Field |
| 7 | Oct 20 | vs | NO | W | 42-34 | State Farm Stadium |
| 8 | Oct 30 | @ | MIN | L | 26-34 | U.S. Bank Stadium |
| 9 | Nov 6 | vs | SEA | L | 21-31 | State Farm Stadium |
| 10 | Nov 13 | @ | Los Angeles Rams | W | 27-17 | SoFi Stadium |
| 11 | Nov 21 | vs | SF | L | 10-38 | Azteca Stadium |
| 12 | Nov 27 | vs | Los Angeles Chargers | L | 24-25 | State Farm Stadium |
| 14 | Dec 12 | vs | NE | L | 13-27 | State Farm Stadium |
| 15 | Dec 18 | @ | DEN | L | 15-24 | Empower Field at Mile High |
| 16 | Dec 25 | vs | TB | L | 16-19 OT | State Farm Stadium |
| 17 | Jan 1 | @ | ATL | L | 19-20 | Mercedes-Benz Stadium |
| 18 | Jan 8 | @ | SF | L | 13-38 | Levi's Stadium |