2010 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 12 | vs | SF | W | 31-6 | Qwest Field |
| 2 | Sep 19 | @ | DEN | L | 14-31 | Invesco Field at Mile High |
| 3 | Sep 26 | vs | San Diego Chargers | W | 27-20 | Qwest Field |
| 4 | Oct 3 | @ | St. Louis Rams | L | 3-20 | Edward Jones Dome |
| 6 | Oct 17 | @ | CHI | W | 23-20 | Soldier Field |
| 7 | Oct 24 | vs | ARI | W | 22-10 | Qwest Field |
| 8 | Oct 31 | @ | Oakland Raiders | L | 3-33 | Oakland-Alameda County Coliseum |
| 9 | Nov 7 | vs | NYG | L | 7-41 | Qwest Field |
| 10 | Nov 14 | @ | ARI | W | 36-18 | University of Phoenix Stadium |
| 11 | Nov 21 | @ | NO | L | 19-34 | Louisiana Superdome |
| 12 | Nov 28 | vs | KC | L | 24-42 | Qwest Field |
| 13 | Dec 5 | vs | CAR | W | 31-14 | Qwest Field |
| 14 | Dec 12 | @ | SF | L | 21-40 | Candlestick Park |
| 15 | Dec 19 | vs | ATL | L | 18-34 | Qwest Field |
| 16 | Dec 26 | @ | TB | L | 15-38 | Raymond James Stadium |
| 17 | Jan 2 | vs | St. Louis Rams | W | 16-6 | Qwest Field |