2010 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 13 | @ | KC | L | 14-21 | Arrowhead Stadium |
| 2 | Sep 19 | vs | JAX | W | 38-13 | Qualcomm Stadium |
| 3 | Sep 26 | @ | SEA | L | 20-27 | Qwest Field |
| 4 | Oct 3 | vs | ARI | W | 41-10 | Qualcomm Stadium |
| 5 | Oct 10 | @ | Oakland Raiders | L | 27-35 | Oakland-Alameda County Coliseum |
| 6 | Oct 17 | @ | St. Louis Rams | L | 17-20 | Edward Jones Dome |
| 7 | Oct 24 | vs | NE | L | 20-23 | Qualcomm Stadium |
| 8 | Oct 31 | vs | Tennessee Titans | W | 33-25 | Qualcomm Stadium |
| 9 | Nov 7 | @ | HOU | W | 29-23 | Reliant Stadium |
| 11 | Nov 22 | vs | DEN | W | 35-14 | Qualcomm Stadium |
| 12 | Nov 28 | @ | IND | W | 36-14 | Lucas Oil Stadium |
| 13 | Dec 5 | vs | Oakland Raiders | L | 13-28 | Qualcomm Stadium |
| 14 | Dec 12 | vs | KC | W | 31-0 | Qualcomm Stadium |
| 15 | Dec 16 | vs | SF | W | 34-7 | Qualcomm Stadium |
| 16 | Dec 26 | @ | CIN | L | 20-34 | Paul Brown Stadium |
| 17 | Jan 2 | @ | DEN | W | 33-28 | Invesco Field at Mile High |