2001 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 9 | vs | Washington Redskins | W | 30-3 | Qualcomm Stadium |
| 2 | Sep 23 | @ | DAL | W | 32-21 | Texas Stadium |
| 3 | Sep 30 | vs | CIN | W | 28-14 | Qualcomm Stadium |
| 4 | Oct 7 | @ | CLE | L | 16-20 | Cleveland Browns Stadium |
| 5 | Oct 14 | @ | NE | L | 26-29 OT | Foxboro Stadium |
| 6 | Oct 21 | vs | DEN | W | 27-10 | Qualcomm Stadium |
| 7 | Oct 28 | vs | BUF | W | 27-24 | Qualcomm Stadium |
| 8 | Nov 4 | vs | KC | L | 20-25 | Qualcomm Stadium |
| 9 | Nov 11 | @ | DEN | L | 16-26 | Invesco Field at Mile High |
| 10 | Nov 18 | @ | Oakland Raiders | L | 24-34 | Network Associates Coliseum |
| 11 | Nov 25 | vs | ARI | L | 17-20 | Qualcomm Stadium |
| 12 | Dec 2 | @ | SEA | L | 10-13 OT | Husky Stadium |
| 13 | Dec 9 | @ | PHI | L | 14-24 | Veterans Stadium |
| 14 | Dec 15 | vs | Oakland Raiders | L | 6-13 | Qualcomm Stadium |
| 15 | Dec 23 | @ | KC | L | 17-20 | Arrowhead Stadium |
| 16 | Dec 30 | vs | SEA | L | 22-25 | Qualcomm Stadium |