2010 Schedule & Results
Regular Season
| Wk | Date | Opponent | Result | Score | Stadium | |
|---|---|---|---|---|---|---|
| 1 | Sep 12 | vs | MIA | L | 10-15 | Ralph Wilson Stadium |
| 2 | Sep 19 | @ | GB | L | 7-34 | Lambeau Field |
| 3 | Sep 26 | @ | NE | L | 30-38 | Gillette Stadium |
| 4 | Oct 3 | vs | NYJ | L | 14-38 | Ralph Wilson Stadium |
| 5 | Oct 10 | vs | JAX | L | 26-36 | Ralph Wilson Stadium |
| 7 | Oct 24 | @ | BAL | L | 34-37 OT | M&T Bank Stadium |
| 8 | Oct 31 | @ | KC | L | 10-13 OT | Arrowhead Stadium |
| 9 | Nov 7 | vs | CHI | L | 19-22 | Rogers Centre |
| 10 | Nov 14 | vs | DET | W | 14-12 | Ralph Wilson Stadium |
| 11 | Nov 21 | @ | CIN | W | 49-31 | Paul Brown Stadium |
| 12 | Nov 28 | vs | PIT | L | 16-19 OT | Ralph Wilson Stadium |
| 13 | Dec 5 | @ | MIN | L | 14-38 | Mall of America Field |
| 14 | Dec 12 | vs | CLE | W | 13-6 | Ralph Wilson Stadium |
| 15 | Dec 19 | @ | MIA | W | 17-14 | Sun Life Stadium |
| 16 | Dec 26 | vs | NE | L | 3-34 | Ralph Wilson Stadium |
| 17 | Jan 2 | @ | NYJ | L | 7-38 | New Meadowlands Stadium |