SF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Brock Purdy | 11/18 | 94 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Jordan Mason | 13 | 78 | 0 |
| Christian McCaffrey | 7 | 53 | 0 |
| Isaac Guerendo | 4 | 19 | 1 |
| Brock Purdy | 2 | 4 | 0 |
| Kyle Juszczyk | 1 | -1 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Jauan Jennings | 3/5 | 56 | 0 |
| Deebo Samuel Sr. | 4/5 | 20 | 0 |
| Christian McCaffrey | 2/3 | 14 | 0 |
| George Kittle | 1/2 | 7 | 0 |
| Ricky Pearsall | 0/1 | 0 | 0 |
| Isaac Guerendo | 1/1 | -3 | 0 |
BUF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Josh Allen | 13/17 | 148 | 2 | 0 |
| Mitchell Trubisky | 1/1 | 4 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| James Cook | 14 | 107 | 1 |
| Ray Davis | 11 | 63 | 1 |
| Ty Johnson | 5 | 28 | 0 |
| Josh Allen | 3 | 18 | 1 |
| Curtis Samuel | 1 | 7 | 0 |
| Mitchell Trubisky | 4 | -3 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Dawson Knox | 2/2 | 56 | 0 |
| Khalil Shakir | 4/7 | 30 | 0 |
| Quintin Morris | 1/1 | 14 | 0 |
| James Cook | 1/1 | 13 | 0 |
| Amari Cooper | 3/3 | 12 | 0 |
| Ty Johnson | 1/1 | 9 | 0 |