PIT
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Mason Rudolph | 22/39 | 229 | 2 | 1 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Jaylen Warren | 8 | 38 | 0 |
| Najee Harris | 12 | 37 | 0 |
| Mason Rudolph | 2 | 16 | 0 |
| George Pickens | 1 | 15 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Pat Freiermuth | 5/8 | 76 | 0 |
| George Pickens | 5/11 | 50 | 0 |
| Diontae Johnson | 4/7 | 48 | 1 |
| Jaylen Warren | 2/2 | 16 | 0 |
| Najee Harris | 2/3 | 15 | 0 |
| Allen Robinson | 2/3 | 12 | 0 |
BUF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Josh Allen | 21/30 | 203 | 3 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| James Cook | 18 | 79 | 0 |
| Josh Allen | 8 | 74 | 1 |
| Ty Johnson | 8 | 26 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Dalton Kincaid | 3/6 | 59 | 1 |
| Stefon Diggs | 7/9 | 52 | 0 |
| Deonte Harty | 1/1 | 34 | 0 |
| Khalil Shakir | 3/3 | 31 | 1 |
| Latavius Murray | 2/2 | 13 | 0 |
| Dawson Knox | 1/2 | 9 | 1 |