SF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Jimmy Garoppolo | 20/33 | 334 | 1 | 1 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Carlos Hyde | 14 | 78 | 1 |
| Matt Breida | 12 | 27 | 0 |
| Jimmy Garoppolo | 5 | -3 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Marquise Goodwin | 6/12 | 106 | 0 |
| Garrett Celek | 2/4 | 67 | 1 |
| Kyle Juszczyk | 3/4 | 64 | 0 |
| Kendrick Bourne | 2/2 | 29 | 0 |
| Aldrick Robinson | 2/2 | 27 | 0 |
| Louis Murphy | 1/2 | 20 | 0 |
HOU
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| T.J. Yates | 14/26 | 175 | 2 | 0 |
| Tom Savage | 6/12 | 63 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Lamar Miller | 17 | 53 | 0 |
| T.J. Yates | 3 | 31 | 0 |
| Andre Ellington | 3 | 6 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| DeAndre Hopkins | 11/16 | 149 | 2 |
| Will Fuller | 3/5 | 26 | 0 |
| DeAndrew White | 1/6 | 24 | 0 |
| Stephen Anderson | 2/6 | 16 | 0 |
| Andre Ellington | 1/2 | 16 | 0 |
| Lamar Miller | 2/2 | 7 | 0 |