SF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Colin Kaepernick | 13/29 | 187 | 1 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Colin Kaepernick | 8 | 66 | 0 |
| Carlos Hyde | 14 | 52 | 0 |
| Mike Davis | 5 | 13 | 0 |
| Shaun Draughn | 1 | 2 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Torrey Smith | 3/7 | 76 | 1 |
| Quinton Patton | 4/7 | 52 | 0 |
| Vance McDonald | 2/2 | 25 | 0 |
| Rod Streater | 1/1 | 16 | 0 |
| Jeremy Kerley | 2/7 | 12 | 0 |
| Mike Davis | 1/3 | 6 | 0 |
BUF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Tyrod Taylor | 16/25 | 179 | 2 | 0 |
| EJ Manuel | 0/2 | 0 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| LeSean McCoy | 19 | 140 | 3 |
| Tyrod Taylor | 8 | 68 | 0 |
| Mike Gillislee | 6 | 61 | 1 |
| Jonathan Williams | 5 | 21 | 0 |
| EJ Manuel | 3 | 11 | 0 |
| Reggie Bush | 2 | 6 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Charles Clay | 5/7 | 52 | 0 |
| Robert Woods | 5/6 | 44 | 1 |
| Justin Hunter | 1/3 | 30 | 1 |
| Nick O'Leary | 2/2 | 29 | 0 |
| Marquise Goodwin | 2/4 | 22 | 0 |
| LeSean McCoy | 1/2 | 2 | 0 |