SF
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Alex Smith | 15/22 | 206 | 3 | 1 |
| Shaun Hill | 6/11 | 45 | 0 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Frank Gore | 13 | 32 | 0 |
| Alex Smith | 2 | 16 | 0 |
| Josh Morgan | 1 | 6 | 0 |
| Glen Coffee | 2 | 3 | 0 |
| Shaun Hill | 1 | 2 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Vernon Davis | 7/11 | 93 | 3 |
| Josh Morgan | 4/4 | 62 | 0 |
| Michael Crabtree | 5/6 | 56 | 0 |
| Isaac Bruce | 2/6 | 23 | 0 |
| Frank Gore | 2/3 | 15 | 0 |
| Delanie Walker | 1/1 | 2 | 0 |
HOU
Passing
| Player | C/A | YDS | TD | INT |
|---|---|---|---|---|
| Matt Schaub | 20/30 | 264 | 2 | 0 |
Rushing
| Player | ATT | YDS | TD |
|---|---|---|---|
| Steve Slaton | 18 | 67 | 1 |
| Chris Brown | 4 | 14 | 0 |
| Matt Schaub | 5 | 9 | 0 |
Receiving
| Player | REC | YDS | TD |
|---|---|---|---|
| Owen Daniels | 7/9 | 123 | 1 |
| Andre Johnson | 2/4 | 62 | 0 |
| Kevin Walter | 3/3 | 29 | 0 |
| Steve Slaton | 4/6 | 22 | 1 |
| Andre Davis | 1/2 | 14 | 0 |
| David Anderson | 2/2 | 10 | 0 |